Long before Wild Wild West and steampunk, there was Tomahawk, ostensibly a series about a small squad of trailblazing fighting frontiersmen (the Rip-Roaring Rangers!) during the Revolutionary War.
Tomahawk wasn't the best-written series nor did it have the best art, but it holds the number one spot of being the most bee-zarre mainstream comic title of the Silver Age...As you can see by the covers pictured here. You could call Tomahawk the lone example of blackpowder punk, however, it was very successful, running for close to 20 years. The stories obviously had to have taken place in an alternate timeline and one reason they worked is that everything was treated very seriously. The series could have easily gone all Lost In Space, but amazingly, it never did.